Table 2.
Final body weight, weight gain, adiposity index, and food and energy intake of rats from all experimental groups
| 6 months | 12 months | 18 months | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| C | HFD | ER | C | HFD | ER | C | HFD | ER | HF/ER | |
| Final BW (g) | 602.5 ± 13.5 | 656.1 ± 27.5 | 444.4 ± 5.1ab | 715.6 ± 27.2a | 763.1 ± 34.4b | 532.6 ± 11.6cde | 748.6 ± 33.8a | 888.8 ± 91.4b | 551.4 ± 20.6cfg | 681.6 ± 16.1h |
| BW gain (g) | 290.1 ± 18.2 | 288.7 ± 18.1 | 161.5 ± 10.8ab | 416.8 ± 32.8a | 474.7 ± 27.8b | 231.1 ± 13.0cde | 416.2 ± 38.6a | 605.6 ± 85.1b | 236.4 ± 17.0cfg | 365.8 ± 32.4gh |
| Adiposity indexj (%) | 6.2 ± 0.8 | 16.1 ± 1.8a | 4.9 ± 0.4b | 6.5 ± 0.5 | 12.2 ± 0.9d | 7.3 ± 0.4ce | 6.0 ± 0.8 | 11.8 ± 0.9f | 7.2 ± 0.7cg | 10.3 ± 0.7fh |
| Food intake (g week−1) | 199.8 ± 7.8 | 132.9 ± 10.6a | 147.0ia | 193.0 ± 10.0 | 139.8 ± 9.1d | 147.0id | 202.5 ± 7.5 | 138.5 ± 5.0f | 147.0if | 138.4 ± 8.8k, 147.0if |
| Energy intake (kJ week−1) | 2,417.4 ± 94.4 | 2,591.6 ± 206.7 | 1,778.7iab | 2,335.3 ± 121.0 | 2,726.1 ± 177.5 | 1,778.7ide | 2,450.3 ± 90.8 | 2,700.8 ± 97.5 | 1778.7ifg | 2,706.6 ± 171.6k, 1,778.7i |
Data are presented as mean ± SEM
BW body weight, C control group, HFD high-fat diet, ER energy-restricted group, HF/ER high-fat diet-fed group of rats that were energy-restricted from 12 to 18 months
aP < 0.05 vs. 6-month C; bP < 0.05 vs. 6-month HFD; cP < 0.05 vs. 6-month ER; dP < 0.05 vs. 12-month C; eP < 0.05 vs. 12-month HFD; fP < 0.05 vs. 18-month C; gP < 0.05 vs. 18-month HFD; hP < 0.05 vs. 18-month ER
iValues refers to fixed amount of food supplied (energy restriction)
jAdiposity index = [(∑ epididymal, mesenteric, retroperitoneal fat pads mass)∙(final body weight)−1]∙100
kHF diet ad libitum intake and energy intake from the beginning of the experiment to 12 months