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. 2012 Jul 27;35(5):1937–1947. doi: 10.1007/s11357-012-9458-y

Table 3.

DNA damage and repair as correlates of MLSP and/or body mass

Trait	Tissue/cell type	Comparison	Correlation with MSLP	Correlation with body mass
PARP activity	Mononuclear blood cells	12 Mammalian species	Positive correlation? (Grube and Burkle 1992)	Positive (Fig. 4)
Excretion of DNA repair productions	Urine	6 Mammalian species	Negative correlation (8oxoGua)	Positive (see Speakman 2005)
Excretion of DNA repair productions	Urine	6 Mammalian species	No correlation (8oxodF, 5-HMUra) (Foksinski et al. 2004)	Positive (see Speakman 2005)
Rate of repair of UV-induced DNA lesions	Fibroblasts	7 Mammalian species	Positive correlation? (Hart and Setlow 1974)	See combined data reanalysis (Fig. 3)
		12 Mammalian species	Positive correlation? (Cortopassi and Wang 1996)	Positive (Fig. 3)
		8 Primate species	Positive correlation? (Hall et al. 1984)	Unknown
		21 Mammalian species	Positive correlation? (Francis et al. 1981)	Unknown
BER	Fibroblasts	8 Mammalian species	Negative correlation (polymerase beta); no correlation (APE) (Brown and Stuart 2007)	None
Double-strand break recognition	Fibroblasts	13 Mammalian species	Positive correlation^a,b (Lorenzini et al. 2009)	No correlation^a (Lorenzini et al. 2009)

^aCorrected for phylogeny

^bCorrected for body mass