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. 2013 Aug 3;3(9):618–632. doi: 10.7150/thno.6810

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© Ivyspring International Publisher. This is an open-access article distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by-nc-nd/3.0/). Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited.

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Fig 7 — Specificity of uPAR imaging by ⁶⁴Cu-CB-TE2A-PA-AE105 targeting. Representative sagittal PET/CT images for ⁶⁴Cu-CB-TE2A-PA-AE105 and its corresponding inactive control peptide ⁶⁴Cu-CB-TE2A-PA-AE105^mut are shown after 1h (panel A). White arrows indicate location of the tumors. The corresponding quantitative ROI analysis of tumor and liver are shown (panel B). Levels of uPAR expression determined by ELISA in resected tumor lysates from mice sacrificed after termination of each imaging experiment are shown in (panel C). (n = 6 tumors (3 mice in each group). *** p<0.001.