Table 1.
LDCT in lung cancer screening
| Trial Name | Study design | No. recruited |
Characteristics of participants |
Exsmoker quit (yrs) | Year started | Report date | LC baseline rate (LDCT) | Stage I Cancer at Baseline | ||
|---|---|---|---|---|---|---|---|---|---|---|
| Age | Sex | Smoker(PkYr) | ||||||||
|
NLST [47] |
LDCT vs CXR |
53454 |
55–74 |
M/F |
>=30 |
<15 |
2002 |
2011 |
1.0% |
63.0% |
|
NELSON [42,95] |
LDCT vs UC |
15822 |
50–75 |
M/F |
15–18.75 |
<10 |
2003 |
2016 |
0.9% |
63.9% |
|
ITALUNG [39] |
LDCT vs UC |
3206 |
55–69 |
M/F |
>=20 |
<10 |
2004 |
NR |
1.5% |
47.6% |
|
DEPISCAN [38] |
LDCT vs CXR |
765 |
50–75 |
M/F |
>=15 |
<15 |
2002 |
2006 |
2.38% |
0.9% |
|
DANTE [37,96] |
LDCT vs UC |
2472 |
60–74 |
M |
>=20 |
<10 |
2001 |
2007 |
2.2% |
57% |
|
DLCST [97] |
LDCT vs UC |
4104 |
50–70 |
M/F |
>=20 |
<10 |
2004 |
2016 |
0.8% |
58.8% |
| LSS [34,36] | LDCT vs CXR | 3318 | 55–77 | M/F | >=30 | <10 | 2000 | 2005 | 1.9% | 53.3% |
LDCT= low-dose computed tomography; CXR=chest X-ray; NC=usual care; M=male; F=female; PkYr=packs/year; yrs=years; f/u=follow-up; NR=not reported; LC=lung cancer.