Table 3.

Therapy and prophylaxis for cytomegalovirus manifestations^a

Therapy/prophylaxis	Drug	Therapeutic regimen
Acute therapy		Duration: at least 3 weeks
First choice	Gancyclovir	2 × 5 mg/kg i.v.
First choice	Foscarnet	2 × 90 mg/kg i.v.
Alternatives	Valgancyclovir	2 × 900 mg p.o.
	Gancyclovir + Foscarnet	2 × 5 mg/kg i.v. 2 × 90 mg/kg i.v.
Maintenance therapy (discontinue when CD4 T-cell count is >100–150/μl for >6 months)
First choice	Valgancyclovir	2 × 450 mg p.o
Alternatives	Foscarnet	1 × 120 mg/kg i.v. on 5 days/week
	Cidofovir	1 × 5 mg/kg i.v. every 2 weeks (plus Probenecid)
	Gancyclovir	3 × 10 mg/kg i.v. on 3 days/week 1 × 5 mg/kg i.v. on 5 days/week
Primary prophylaxis		Not recommended

^aUnless specified otherwise, daily doses