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. Author manuscript; available in PMC: 2013 Sep 18.
Published in final edited form as: Biomed Pharmacother. 2010 Nov 4;64(10):723–732. doi: 10.1016/j.biopha.2010.10.001

Fig. 2.

Fig. 2

Variations in the backbone n1 (A) or n2 (B) chain length alter the in vitro cytotoxicity of biguanide-based compounds. P4-R5 MAGI cells were exposed to N-9, dextran sulfate (DS), or the indicated PDBG compounds for 2 h and subsequently assayed for viability, which is expressed as a percentage relative to mock-exposed cells. Combined results are depicted from two independent cytotoxicity assays, in which each concentration was examined in duplicate. Error bars indicate the standard deviation for each data point.