Fig. 3.

Backbone linker length changes affect the ability to interfere with infection by HIV-1 strains IIIB or BaL. In a VII assay, dextran sulfate (DS) or the indicated compounds were incubated with cell-free HIV-1 strains (A) IIIB or (B) BaL in the presence of P4-R5 MAGI cells for 2 h at 37 °C. Infectivity remaining after compound exposure is expressed as a percentage relative to cells infected in the absence of compound. Combined results are depicted from two independent assays, in which each concentration was examined in duplicate. Error bars indicate the standard deviation for each data point.