PEHMB (2-6) does not adversely affect the integrity of the mouse cervical epithelium after exposures up to 8 h. Female Swiss Webster mice were inoculated intravaginally with (A) diluent (water) only or 1% solutions of unformulated (B) N–9, (C, E, G, I) PHMB, or (D, F, H, J) PEHMB. Mice were sacrificed at 10 min, 2 h, 4 h, or 8 h following application, and the entire reproductive tract was surgically excised. Formalin-fixed, paraffin-embedded tissues were stained with hematoxylin and eosin. Representative fields from the cervical epithelium of each treatment group are shown.