Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Partial embryonic lethality in SnoNm/m embryos
| Stage | SnoNm/m | SnoN+/m | SnoN+/+ | % |
| Postnatal | 43 | 127 | 100 | 15.9: 47.0: 37.1 |
| E16.5–E18.5 | 10 | 31 | 20 | 16.4: 50.8: 32.8 |
| E12.5 | 6 | 22 | 10 | 15.8: 57.9: 26.3 |
| E10.5–E11.5 | 15 | 28 | 17 | 25.0: 46.7: 28.3 |
Partial lethality of the SnoNm/m embryos occurs between E11.5 and E12.5. Offspring resulting from heterozygous intercrosses were genotyped at various embryonic developmental stages. Significant deviation from the Mendelian ratio is detected after E11.5.
