. 2013 Sep 3;2013:756302. doi: 10.1155/2013/756302

Table 4.

Frequency of the molecular markers investigated with respect to the EMP3 methylation status.

Tumor type	EMP3 methylation status (n)	IDH1/IDH2 mutations	MGMT methylation	EGFR amplification	Total 1p/19 codeletion	TP53 mutations
Tumor type	EMP3 methylation status (n)	n (%)	n (%)	n (%)	n (%)	n (%)
PA	Methylated (4)	0/4 (0)	0/4 (0)	1/3 (33.3)	0/4 (0)	0/4 (0)
PA	Unmethylated (14)	1/14 (7.1)	4/14 (28.6)	1/10 (10)	0/12 (0)	3/14 (21.4)
DA and GA	Methylated (3)	3/3 (100)	1/2 (50)	0/3 (0)	0/2 (0)	2/3 (66.7)
DA and GA	Unmethylated (6)	1/6 (16.7)	2/6 (33.3)	0/6 (0)	1/6 (16.7)	2/5 (40)
AA	Methylated (3)	3/3 (100)	1/1 (100)	0/3 (0)	0/3 (0)	2/2 (100)
AA	Unmethylated (5)	1/5 (20)	1/4 (25)	1/4 (25)	0/2 (0)	0/3 (0)
pGBM	Methylated (5)	0/5 (0)	2/5 (40)	2/4 (50)	0/5 (0)	1/4 (25)
pGBM	Unmethylated (57)	0/53 (0)	24/57 (42.1)	21/54 (38.9)	0/57 (0)	12/38 (31.6)
sGBM	Methylated (3)	3/3 (100)	3/3 (100)	0/3 (0)	0/3 (0)	2/3 (66.7)
sGBM	Unmethylated (0)	— (—)	— (—)	— (—)	— (—)	— (—)
OA	Methylated (9)	9/9 (100)	4/6 (66.7)	0/6 (0)	0/8 (0)	4/6 (66.7)
OA	Unmethylated (3)	1/3 (33.3)	1/1 (100)	0/1 (0)	0/2 (0)	1/1 (100)
AOA	Methylated (5)	3/5 (60)	4/5 (80)	1/5 (20)	1/5 (20)	1/1 (100)
AOA	Unmethylated (3)	1/1 (100)	2/3 (66.7)	1/1 (100)	0/3 (0)	1/1 (100)
O	Methylated (33)	29/33 (77.8)	18/25 (13.3)	1/29 (3.4)	18/33 (54.5)	5/19 (26.3)
O	Unmethylated (9)	5/9 (55.5)	5/9 (55.9)	1/9 (11.1)	4/9 (44.4)	1/5 (20)
AO	Methylated (13)	8/13 (61.5)	9/13 (69.2)	1/13 (7.7)	8/13 (61.5)	4/16 (40)
AO	Unmethylated (18)	5/16 (31.2)	12/16 (75)	8/16 (50)	3/16 (18.8)	2/13 (15.4)

PA: pilocytic astrocytoma, DA: diffuse astrocytoma, GA: gemistocytic astrocytoma, AA: anaplastic astrocytoma, GBM: glioblastoma multiforme, O: oligodendroglioma, AO: anaplastic oligodendroglioma, OA: oligoastrocytoma, AOA: anaplastic oligoastrocytoma.