Table 2.

Midkine expression prechemotherapy compared to postchemotherapy.

	Nuclear Score			Cytoplasmic score
	Pre-chemo	Post-chemo	P	Pre-chemo	Post-chemo	P
All biopsies*	2.3 ± 1.1	1.7 ± 1.2	0.15	0.9 ± 1.1	2.2 ± 1.3	0.005
Matched biopsies**	2.1 ± 1.3	1.9 ± 1.3	0.74	0.4 ± 0.8	2.3 ± 1.2	<0.001

*Comparison based on 20 prechemotherapy biopsies and 12 postchemotherapy biopsies.

**Comparison based only on the 10 patients with matched pre- and postchemotherapy biopsies available for analysis.