Table 1.
Characteristics of Patients with Early Stage NSCLC Stratified by Treatment
| Overall Cohort N = 10,923 | SABR | Conventional Radiation | Sublobar Resection | Lobectomy | Observation | ||
|---|---|---|---|---|---|---|---|
|
|
|||||||
| Variable | N (%) | N (%) | N (%) | N (%) | N (%) | N (%) | P>X2 |
| Sociodemographics | |||||||
| Age, y | |||||||
| 66–69 | 1939 (18) | 11 (9) | 163 (10) | 234 (18) | 1408 (22) | 123 (9) | <.001 |
| 70–74 | 3043 (28) | 20 (16) | 338 (21) | 362 (28) | 2055 (31) | 28 (19) | |
| 75–79 | 3115 (29) | 29 (23) | 428 (27) | 392 (31) | 1907 (29) | 359 (26) | |
| ≥80 | 2826 (26) | 64 (52) | 684 (42) | 289 (23) | 1161 (18) | 628 (46) | |
| Race | |||||||
| White | >9790b (>90) | >11 (>90) | 1416 (88) | 1184 (93) | 5927 (91) | 1151 (84) | <.001 |
| Black/Other | <1135 (<10) | <11 (<10) | 197 (12) | 93 (7) | 604 (10) | 227 (16) | |
| Sex | |||||||
| Male | 5016 (46) | 49 (40) | 753 (47) | 571 (45) | 3011 (46) | 632 (46) | 0.52 |
| Female | 5907 (54) | 75 (60) | 860 (53) | 706 (55) | 3520 (54) | 746 (54) | |
| Comorbidity | |||||||
| 0 | 3940 (36) | 28 (23) | 387 (24) | 339 (27) | 2814 (43) | 372 (27) | <.001 |
| 1 | 3466 (32) | 42 (34) | 503 (31) | 447 (35) | 2042 (31) | 432 (31) | |
| ≥2 | 3151 (29) | 54 (44) | 652 (40) | 457 (36) | 1495 (23) | 493 (36) | |
| missing | 366 (3) | ||||||
| Educational Attainment of zip code or county | |||||||
| Quartile 1 | 2731 (25) | 34 (27) | 315 (20) | 323 (25) | 1781 (27) | 278 (20) | <.001 |
| Quartile 2 | 2738 (25) | 29 (23) | 396 (25) | 339 (27) | 1651 (25) | 323 (23) | |
| Quartile 3 | 2720 (25) | 36 (29) | 422 (26) | 323 (25) | 1597 (24) | 342 (25) | |
| Quartile 4 | 2734 (25) | 25 (20) | 480 (30) | 292 (23) | 1502 (23) | 435 (32) | |
| Median income of zip code or county | |||||||
| Quartile 1 | 2741 (25) | 27 (22) | 513 (32) | 284 (22) | 1494 (23) | 423 (31) | <.001 |
| Quartile 2 | 2741 (25) | 38 (31) | 423 (26) | 322 (25) | 1603 (25) | 355 (26) | |
| Quartile 3 | 2724 (25) | 31 (25) | 379 (23) | 340 (27) | 1627 (25) | 347 (25) | |
| Quartile 4 | 2717 (25) | 28 (23) | 298 (18) | 331 (26) | 1807 (28) | 253 (18) | |
| Tumor Characteristics | |||||||
| Tumor size | |||||||
| ≤ 2.0 cm | 4393 (40) | 48 (39) | 437 (27) | 820 (64) | 2723 (42) | 365 (26) | <.001 |
| 2.1 – 3.0 cm | 3595 (33) | 48 (39) | 576 (36) | 316 (25) | 2188 (34) | 467 (34) | |
| 3.1 – 5.0 cm | 2935 (27) | 28 (23) | 600 (37) | 141 (11) | 1620 (25) | 546 (40) | |
| Histology | |||||||
| NSCLC, NOS | 1389 (13) | 34 (27) | 475 (29) | 84 (7) | 373 (6) | 423 (31) | <.001 |
| Adenocarcinoma | 5763 (53) | 53 (43) | 500 (31) | 749 (59) | 3931 (60) | 530 (38) | |
| Squamous | 3361 (31) | 36 (29) | 580 (36) | 389 (30) | 1982 (30) | 374 (27) | |
| Grade | |||||||
| Low-intermediate | 5054 (46) | 31 (25) | 329 (20) | 690 (54) | 3722 (57) | 282 (20) | <.001 |
| High | 3477 (32) | 23 (19) | 453 (28) | 431 (34) | 2215 (34) | 355 (26) | |
| Unknown | 2392 (22) | 70 (56) | 831 (52) | 156 (12) | 594 (9) | 741 (54) | |
| Laterality | |||||||
| Right | 6354 (58) | 57 (46) | 941 (58) | 716 (56) | 3866 (59) | 774 (56) | <.001 |
| Left | 4567 (42) | 67 (54) | 672 (42) | 561 (44) | 2665 (41) | 602 (44) | |
| Subsite in lung | |||||||
| Upper lobe | 6599 (60) | 76 (61) | 995 (62) | 782 (61) | 3995 (61) | 751 (54) | <.001 |
| Middle lobe | 530 (5) | <11 (<10) | >73 (<10) | 39 (3) | 336 (5) | 71 (5) | |
| Lower lobe | 3461 (32) | 36 (29) | 468 (29) | 425 (33) | 2067 (32) | 465 (34) | |
| Bronchus | 45 (<1) | ||||||
| Other | 288 (3) | ||||||
| PET scanning | |||||||
| Not Perfomed | 5785 (53) | 32 (26) | 741 (46) | 684 (54) | 3407 (52) | 921 (67) | <.001 |
| Performed | 5138 (47) | 92 (74) | 872 (54) | 593 (46) | 3124 (48) | 457 (33) | |
| Treatment Characteristics | |||||||
| Number of lymph nodes sampled | |||||||
| 0 | 4160 (38) | >110 (>90) | 1552 (96) | 736 (58) | 432 (7) | 1321 (96) | <.001 |
| 1 or more | 6741 (62) | <11 (<10) | 55 (4) | 538 (42) | 6095 (93) | 49 (4) | |
| Unknown | 22 (<1) | ||||||
Abbrev: SABR (stereotactic ablative radiation); NSCLC, NOS (Nonsmall-cell lung cancer, not otherwise specified).
b
Exact figures not specified in some cells due to SEER-Medicare terms of use.