Table 4.
Putative transcription factor binding sites spanning CpG83 and CpG85.
| CpG | Sequence† | Strand | Transcription factor | Factor name |
|---|---|---|---|---|
| 85 | GTTTGTTCTT | (+) | HNF1A (TCF1) | Hepatocyte nuclear factor 1 homeobox A (transcription factor 1) |
| HNF1B (TCF2) | Hepatocyte nuclear factor 1 homeobox B (transcription factor 2) | |||
| HNF1C | – | |||
|
| ||||
| GTTTGTTTT | (+) | HNF-3 (FOXM1) | Hepatocyte nuclear factor 3 (forkhead box M1) | |
| HNF3A (FOXA1) | Hepatocyte nuclear factor 3A (forkhead box A1) | |||
| HNF3B (FOXA2) | Hepatocyte nuclear factor 3B (forkhead box A2) | |||
|
| ||||
| 83 | GGAA | (−) | ISGF3 (IRF9) | Interferon-stimulated gene factor 3 (interferon regulatory factor 9) |
| NF-AT2 | Nuclear factor of activated T cells 2 | |||
| NF-AT3 | Nuclear factor of activated T cells 3 | |||
| NF-AT4 | Nuclear factor of activated T cells 4 | |||
| ELF-1 | E74-like factor 1 | |||
|
| ||||
| GTCTCTCCCCTT | (+) | SP1 | Specificity protein 1 | |
†
Sequence mismatch underlined. CG sites (or parts thereof) in bold. Transcription factor binding sites (vertebrates) identified using Patch and AliBaba2.1 programs [102].