Table 2.
Agent/intervention | Type of agent/intervention | Type of prevention | Participants | Phase | Completion date | NCT ID |
---|---|---|---|---|---|---|
S-adenosylmethionine (SAMe) | Nutritional supplement | Secondary | Advanced chronic hepatitis C | 2 | Dec 2012 | NCT005134 61 |
Phlebotomy | Iron depletion | Secondary | Compensated alcoholic cirrhosis | 3 | Jun 2017 | NCT013427 05 |
PEG interferon alpha-2b + ribavirin | Immune modulator, anti-viral | Tertiary | HCV-related HCC after resection | 4 | Feb 2013 | NCT003756 61 |
Interferon-alpha | Immune modulator | Tertiary | p48-positive HCC after resection | - | Jan 2011 | NCT008389 68 |
Sirolimus | Immune modulator | Tertiary | HCC (exceeding Milan criteria) after liver transplantation | 3 | Aug 2013 | NCT005541 25 |
Sorafenib (STORM trial) | Kinase inhibitor | Tertiary | HCC after resection | 3 | Oct 2014 | NCT006927 70 |
Gefitinib | Kinase inhibitor | Tertiary | HCC after resection | 2 | Dec 2012 | NCT002821 00 |
Thymopentin | Immune modulator | Tertiary | HBV-related HCC after resection | 3 | Feb 2012* | NCT004606 81 |
Sustained released 5-FU ± cisplatin (TACE) | Cytotoxic agent | Tertiary | HCC after resection | - | Dec 2010* | NCT008178 95 |
Epirubicin and lipiodol (TACE) | Cytotoxic agent | Tertiary | HCC after resection | 2 | Dec 2010* | NCT008200 53 |
Capecitabine (systemic) | Cytotoxic agent | Tertiary | HCC after resection | 2/3 | Jul 2012* | NCT005615 22 |
Gemcitabine + Oxaliplatin (systemic) (vs. doxorubicin + 5-FU + cisplatin) | Cytotoxic agent | Tertiary | HCC after liver transplantation | - | Dec 2010* | NCT011250 20 |
Gemcitabine + Oxaliplatin (sytemic) (vs. arterial lipiodol) | Cytotoxic agent | Tertiary | HCC after resection/ablation | 3 | Jun 2014 | NCT004703 40 |
HCC: hepatocellular carcinoma, HCV: hepatitis C virus, HBV: hepatitis B virus, TACE: transarterial chemoembolization, NCT ID: National Clinical Trials Identifier
Current recruitment status is unknown in the database From www.ClinicalTrials.gov accessed June 2012