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. Author manuscript; available in PMC: 2014 Aug 15.
Published in final edited form as: J Am Chem Soc. 2013 Jul 30;135(32):12122–12134. doi: 10.1021/ja406223k

Figure 8.

Figure 8

Flowchart for the prediction of regioselectivity of alkylsulfinate-derived radical functionalization of pyridines. Color code: green circles, sites activated to nucleophilic attack; red circles, sites subject to a functional group induced deactivating influence; yellow circles, otherwise activated sites that have reduced or negligible activity due to substituent-induced deactivation. The size of the circle represents relative degree of activation within the same molecule. Further examples of regioselectivity prediction are in the Supporting Information.