Table 3.
Baseline Characteristics of 91 patients with moderate-severe mitral regurgitation Randomized to CABG who Received CABG with versus without Mitral Valve Repair.
| Characteristic | No MV Repair (n=42) |
MV Repair (n=49) |
P Value |
|---|---|---|---|
| Age, median (25th, 75th), yrs. | 64 (56, 70) | 60 (54, 68) | 0.276 |
| Male, no. (%) | 37 (88) | 44 (90) | 1.000 |
| Previous MI, no. (%) | 31 (74) | 40 (82) | 0.369 |
| Hyperlipidemia, no. (%) | 19 (45) | 35 (73) | 0·008 |
| Hypertension, no. (%) | 21 (50) | 29 (59) | 0.380 |
| Diabetes, no. (%) | 23 (55) | 13 (27) | 0.006 |
| Chronic renal disease, no. (%) | 2 (5) | 5 (10) | 0.445 |
| Previous stroke, no. (%) | 3 (7) | 5 (10) | 0.721 |
| Previous PCI, no. (%) | 4 (10) | 14 (29) | 0.023 |
| Previous CABG, no. (%) | 2 (5) | 2 (4) | 1.000 |
| Current CCS angina class, no. (%) | 0.119 | ||
| 0 | 13 (31) | 23 (47) | |
| 1 | 3 (7) | 5 (10) | |
| 2 | 23 (55) | 17 (35) | |
| 3 | 1 (2) | 4 (8) | |
| 4 | 2 (5) | 0 (0) | |
| Highest NYHA class in last 3 months, no. (%) | 0.527 | ||
| I | 2 (5) | 2 (4) | |
| II | 14 (33) | 13 (27) | |
| III | 19 (45) | 25 (51) | |
| IV | 7 (17) | 9 (18) | |
| Region, no. (%) | <0.001 | ||
| Europe | 13 (31) | 35 (71) | |
| US and Canada | 9 (21) | 8 (16) | |
| Other | 20 (48) | 6 (12) | |
| Treatment distribution by region, no. (%) | <0.001 | ||
| Europe | 13 (27) | 35 (73) | |
| US and Canada | 9 (53) | 8 (47) | |
| Other | 20 (77) | 6 (23) | |
| Risk at randomization | 19 (15, 24) | 17 (9, 23) | 0.282 |
| CAD distribution, no. of vessels stenosed (75% criterion), No. (%) | 0.909 | ||
| 1 | 9 (21) | 12 (24) | |
| 2 | 17 (41) | 18 (37) | |
| 3 | 16 (38) | 19 (39) | |
| Left main (≥50% stenosis), no. (%) | 2 (5) | 1 (2) | 0.593 |
| Proximal LAD (≥75% stenosis), no. (%) | 26 (62) | 29 (59) | 0.791 |
| Duke CAD index, median (25th, 75th), 0–100 | 59 (43, 77) | 52 (37, 77) | 0.697 |
| LV ejection fraction, median (25th, 75th), % | 30 (25, 35) | 22 (19, 28) | <0.001 |
| ESVI, median (25th, 75th), mL/m2 | 75 (54, 109) | 97 (69, 135) | 0.008 |
| Six-minute walk test | |||
| Able to perform, no. (%) | 36 (88) | 39 (80) | 0.298 |
| Distance walked, median (25th, 75th), m | 289 (218, 385) | 353 (306, 400) | 0.042 |
Abbreviations: CABG, coronary artery bypass grafting; CAD, coronary artery disease; CCS, Canadian Cardiovascular Society; ESVI, end-systolic volume index; LAD, left anterior descending; LV, left ventricular; MI, myocardial infarction; MV, mitral valve; NYHA, New York Heart Association; PCI, percutaneous coronary intervention.