Table 4.
Operative Conduct and perioperative events by baseline mitral regurgitation severity of 555 patients randomized to CABG and treated surgically
| Surgical Data | None or Trace MR (N=198) |
Mild MR (N=266) |
Moderate-Severe MR (N=91) |
P Value |
|---|---|---|---|---|
| Number of distal anastomoses | 3 (2, 3) | 3 (2, 3) | 3 (2, 4) | 0.019 |
| Number of distal anastomoses, no. (%) | 0.019 | |||
| 0–1 | 25 (13) | 35 (13) | 10 (11) | |
| 2–3 | 133 (67) | 167 (63) | 49 (54) | |
| ≥4 | 40 (20) | 63 (24) | 32 (35) | |
| Arterial conduits ≥1, no. (%) | 184 (93) | 241 (91) | 80 (88) | 0.366 |
| Types of procedures on mitral valve, no. (%) | <0.001 | |||
| None | 196 (99) | 254 (95) | 42 (46) | |
| Repair | 2 (1) | 12 (5) | 48 (53) | |
| Bioprosthesis | 0 | 0 | 1 (1) | |
| Off-pump, no. (%) | 45 (23) | 54 (20) | 17 (19) | 0.695 |
| Cardioplegia, no. (%) | 0.309 | |||
| None | 55 (28) | 71 (27) | 24 (26) | |
| Crystalloid | 43 (22) | 66 (25) | 13 (14) | |
| Blood | 93 (47) | 119 (45) | 53 (58) | |
| Both | 6 (3) | 8 (3) | 1 (1) | |
| Time on aorta cross-clamp, median (25th, 75th), min | 48 (35, 64) | 51 (34, 70) | 79 (56, 110) | <0.0001 |
| Time on bypass pump, median (25th, 75th), min | 81 (63, 105) | 88 (67, 116) | 123 (95, 161) | <0.0001 |
| Total time in OR, median (25th, 75th), hrs. | 4.5 (3.8, 5.8) | 4.3 (3.5, 5,5) | 5.5 (4.4, 6.3) | <0.0001 |
| Total intubation time, median (25th, 75th), hrs. | 17 (11, 22) | 15 (11, 22) | 21 (14, 24) | <0.0001 |
| Total time in CCU/ICU, median (25th, 75th), hrs. | 49 (40, 92) | 47 (38, 90) | 91 (54, 155) | <0.0001 |
| Length of hospital stay after surgery, median (25th, 75th), days | 8 (7, 11) | 9 (7, 13) | 9 (7, 14) | 0.024 |
| Hospital stay longer than 30 days after surgery, no. (%) | 6 (3) | 14 (5) | 6 (7) | 0.331 |
| Inotropes for low CO, no. (%) | 67 (34) | 102 (38) | 47 (52) | 0.015 |
| Intraaortic balloon pump, no. (%) | 25 (13) | 40 (15) | 24 (26) | 0.010 |
| Death within 30 days after surgery, no. (%) | 6 (3) | 13 (5) | 7 (8) | 0.214 |
Abbreviations: CCU, cardiac care unit; CO, cardiac output; ICU, intensive care unit; MR, mitral regurgitation; OR, operating room.