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. Author manuscript; available in PMC: 2013 Sep 18.
Published in final edited form as: Trop Med Int Health. 2008 Oct 13;13(11):1400–1404. doi: 10.1111/j.1365-3156.2008.02153.x

Table 1.

The mean of three ONS diameter measurements and CT brain scan reports of paediatric patients with neurological disease

Patient Age
(months)
Diagnosis ONS
diameter
(mm)
Clinical signs of raised
intracranial pressure
CT scan report
Patients with clinically suspected raised ICP
1 108 Meningitis 5.1 Clinical deterioration and
 recovered respiratory arrest
Gross hydrocephalus. Very tight
 brain with loss of gyri/sulci
2 96 SOL 5.7 Moderate papilloedema
Bilateral VI nerve palsies
SOL around lateral ventricles and sella turnica.
 Large ventricles. Obstructive hydrocephalus
3 30 SOL 5.4 Bilateral VI nerve palsies
 and upbeat nystagmus
Obstructive hydrocephaly from
 brainstem glioma
4 19 Coma unknown 5.6 Moderate papilloedema
Dilated unreactive pupils
Not done
5 48 Meningitis 5.4 Moderate papilloedema
Right dilated unreactive pupil
Not done
6 72 Coma unknown 4.9 Mild papilloedema Not done
7 108 TB Meningitis 5.7 Mild papilloedema
Deepening coma
Gross hydrocephalus. Multiple
 granuloma in parenchyma
8 41 SOL 5.0 Dilated unreactive pupils
Absent oculocephalic reflex
Not done
9 144 Hydrocephalus 5.9 Severe papilloedema
VI nerve palsy
Macrocephalic
Ataxic gait
Severe hydrocephalus with aqueduct stenosis
10 15 Suspected poisoning 4.3 Mild papilloedema Not done
11 93 Coma unknown 6.2 Mild papilloedema Cerebral oedema with compression of
 ventricles and basal cistern
12 84 Coma unknown 5.8 Severe papilloedema
Anisocoria
Mild communicating hydrocephalus.
 Left pontine infarct
13 111 Meningitis 5.5 Moderate papilloedema
VI nerve palsy
Unreactive pupils
Not done
14 31 Coma unknown 5.0 Mild papilloedema Severe brain oedema. The ventricles and
 basilar cisterns are compressed
Patients without clinically suspected raised ICP
15 56 Coma unknown 4.4 None Normal
16 28 Meningitis 4.0 None Not done
17 96 SOL. Focal seizures 4.0 None SOL. Astrocytoma? No mass effect
18 96 Brainstem tumour 3.2 None Brainstem tumour. No hydrocephalus
19 11 Coma unknown 3.5 None Not done
20 18 Kwashiorkor
 HIV Convulsions
2.8 None Normal
21 144 Epilepsy
New ataxia
3.6 None Not done

ONS, optic nerve sheath; ICP, intracranial pressure; SOL, space occupying lesion; TB, tuberculosis.