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. Author manuscript; available in PMC: 2014 Jul 24.
Published in final edited form as: J Am Chem Soc. 2013 Jul 12;135(29):10642–10645. doi: 10.1021/ja405950c

Table 2.

Substrate Scope of Aryl and Heteroaryl Halides.a

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(A) Aryl halides
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11a, 67%, X = Br
α/γ = 98:2
11b, 74%, X = Br
α/γ = 97:3
11c, 61%, X = Br
α/γ = 98:2
11g, 81% (95%), X = Br
γ/α > 99:1
11h, 96%, X = Br
γ/α > 99:1
11I, 95%, X = Br
γ/α > 99:1
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11d, (69%), X = Br
α/γ > 99:1
11e, 85%, X = Br
α/γ > 99:1
11f, 75% (84%), X = Br, α/γ = 98:2
(89%), X = CI, α/γ = 98:2
(96%), X = OTf, α/γ = 98:2
11J, 70% (80%), X = Br
γ/α < 99:1
11k, 90%, X = Br
γ/α > 99:1
11I, 90%, (95%), X = Br, γ/α > 99:1
(97%), X = CI, γ/α = 99:1
(95%), X = OTf, γ/α > 99:1

(B) Heteroaryl halides
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11m, 75%, X = Br
α/γ = 99:1
11n, 75%, X = Br
α/γ = 99:1
11o, 86%, X=Br
α/γ > 99:1b
11s, 97%, X = Br
γ/α > 99:1
11t, 85%, X = CI
γ/α > 99:1
11u, 62%c, X = CI
γ/α > 99:1
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11p, 54% (75%), X = Br
α/γ > 99:1b
11q, 85%, X = Br
α/γ > 99:1b
11r, 97%, X = CI
α/γ > 99:1b
11v, 77%, X = CI
γ/α > 99:1
11w, 93%, X = Br
γ/α > 99:1
11x, 78%, X = CI
γ/α > 99:1
a

Yields are of isolated product, see Supporting Information for details; α/γ ratio and yields in parentheses were determined by 1H NMR spectroscopy of the crude reaction mixture using 1,3,5-trimethoxybenzene as an internal standard.

b

L5 was used instead of L6.

c

60 °C.