Table 2.
. Allele frequencies in the RLIP76 gene
| Sequence Change | Allele | Number of hromosomes in Refractory Patients (%) | Number of Chromosomes in Non Refractory Patients (%) | Number in Both Groups (%) | p Value | Test Applied |
|---|---|---|---|---|---|---|
|
| ||||||
| c.160-4G>A | G | 130 (44.5) | 126 (40.6) | 256 (42.5) | 0.3795 | Pearson χ2 |
| A | 162 (55.5) | 184 (59.4) | 346 (57.5) | |||
|
| ||||||
| c.187C>G | C | 2 (0.7) | 1 (0.3) | 3 (0.5) | 0.6135 | Fisher’s exact |
| G | 290 (99.3) | 309 (99.7) | 599 (99.5) | |||
|
| ||||||
| c.1562-38G>A | G | 260 (89.0) | 280 (90.3) | 540 (89.7) | 0.7018 | Pearson χ2 |
| A | 32 (11.0) | 30 (9.7) | 62 (10.3) | |||
|
| ||||||
| c.1670+107G>A | G | 274 (93.8) | 296 (95.5) | 570 (94.7) | 0.4720 | Pearson χ2 |
| A | 18 (6.2) | 14 (4.5) | 32 (5.3) | |||
|
| ||||||
| c.1670+93G>A | G | 288 (98.6) | 304 (98.1) | 592 (98.4) | 0.7530 | Fisher’s exact |
| A | 4 (1.4) | 6 (1.9) | 10 (1.6) | |||
|
| ||||||
| c.1670+96G>A | G | 291 (99.7) | 310 (100.0) | 601 (99.8) | 0.9761 | Fisher’s exact |
| A | 1 (0.3) | 0 (0.0) | 1 (0.2) | |||
|
| ||||||
| c.1670+100C>T | C | 291 (99.7) | 310 (100.0) | 601 (99.8) | 0.9761 | Fisher’s exact |
| T | 1 (0.3) | 0 (0.0) | 1 (0.2) | |||
|
| ||||||
| c.1670+130C>T | C | 262 (89.7) | 283 (91.3) | 545 (90.5) | 0.6059 | Pearson χ2 |
| T | 30 (10.3) | 27 (16.1) | 57 (9.5) | |||
|
| ||||||
| c.1670+131G>C | G | 292 (100.0) | 309 (99.7) | 601 (99.8) | 1.00 | Fisher’s exact |
| C | 0 (0.0) | 1 (0.3) | 1 (0.2) | |||
|
| ||||||
| c.1670+140G>C | G | 292 (100.0) | 309 (99.7) | 601 (99.8) | 1.00 | Fisher’s exact |
| C | 0 (0.0) | 1 (0.3) | 1 (0.2) | |||