Table 2.
Genotype and allele distribution of IL-18 gene in patients and controls.
| IL-18 −607(C/A) | Patients (n = 500) | Controls (n = 500) | OR (95% CI) | p Value |
|---|---|---|---|---|
| Genotype | n (%) | n (%) | ||
| CC | 215 (43.0) | 192 (38.4) | 1.0 Reference | |
| CA | 257 (51.4) | 264 (52.8) | 0.87 (0.66–1.14) | 0.321 |
| AA | 28 (5.6) | 44 (8.8) | 0.57 (0.33–0.98) | 0.040 |
| Allelic | ||||
| C allele | 687 (68.7) | 648 (64.8) | 1.0 Reference | |
| A allele | 313 (31.3) | 352 (35.2) | 0.84 (0.69–1.01) | 0.071 |
OR: odds ratio [OR was calculated by Epi-info Version 3.5.1. (Centers for Disease Control and Prevention, Atlanta, GA, USA); 95% CI: 95% confidence interval; a p value of ≤0.05 was considered significant.