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. 2013 Jun 27;8(2):320–326. doi: 10.3892/mmr.2013.1560

Figure 4.

Figure 4

Dose dependence of ultrasound-targeted microbubble destruction (UTMD) enhancement in adeno-associated virus (AAV) transduction. (A) The enhanced green fluorescent protein (EGFP)-positive ratios of infected HeLa cells 48 h following infection of rAAV2-EGFP with three different multiplicities of infection (MOIs). The data were obtained using flow cytometry conducted in triplicates. (B) The baseline efficiency dependence of the mean enhanced transduction efficiency of HeLa cells. (C) The EGFP-positive ratios of infected NIH/3T3 cells 48 h following infection with rAAV2-EGFP with three different MOIs. (D) The baseline efficiency dependence of the mean enhanced transduction efficiency of NIH/3T3 cells. v.g., vector genome.