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. 2013 Jun 28;8(2):645–649. doi: 10.3892/mmr.2013.1562

Figure 1.

Figure 1

Sphk-1 and TNF-α mRNA expression in young (3 months old) and aged (23 months old) rats following endotoxemia. Total RNA was extracted from liver tissues of Sham and LPS-treated rats. (A) Sphk1 and (B) TNF-α mRNA expression was evaluated by Q-PCR and presented as fold change over GAPDH. Fold change in young Sham rats was set as 1.0. Data are presented as the mean ± SEM and compared by one-way ANOVA and Student-Newman-Keuls method. *P<0.05, vs. Sham, #P<0.05, vs. LPS 3M. Sphk-1, sphingosine kinase-1; LPS, lipopolysaccharide; Q-PCR, quantitative PCR.