Table IV.

Functional follow-up of 3 NS/MPD patients with myeloproliferative evolution.

	NS/MPD1		NS/MPD2		NS/MPD3
Parameters	T0	T1	T0	T1	T0	T1
Age at T0	2 months		10 days		1 month
WBC (/μl)	14,500	8,200	43,500	8,480	20,200	16,000
Monocytes (/μl)	2,500	1,400	5,520	620	2,550	1,280
CD34+ (/μl)	58	150	1,374	13	205	45
Annexin V+ (%)	2.4	7.5	0.2	0.8	1.6	3.0
Hyper-response to GM-CSF	+++	++	+++	No	No	+++
Spontaneous CFU growth	++	++	+	No	No	No
Circulating dysplastic monocytes with myeloid dysplasia	No	+++	++	No	+	No
Hepatosplenomegaly	No	++	No	No	++	No
Thrombocytopenia	No	+++	++	No	No	No

NS/MPD, Noonan syndrome patients with myeloproliferative evolution. T₀, first observation; T₁, observation at 12 months.