Table 3. Associations between the timing of peripheral malaria infection and placental pathology.
Peripheral malaria detected during second trimester | Peripheral malaria detected during third trimester | Peripheral infection at delivery | |
---|---|---|---|
Proportion without placental malaria (%) | 5/230 (2.1) | 5/230 (2.1) | 0/230 (0) |
Proportion with placental malaria (%) | 36/75 (48.0) | 10/75 (13.3) | 3/75 (4.0) |
Odds ratio (95% confidence interval) | 6.8 (4.0-11.2) | 2.1 (1.4-3.2) | NC |
Proportion without hemozoin in the placenta (%) | 5/234 (21.4) | 5/234 (21.4) | 1/234 (0.4) |
Proportion with hemozoin in the placenta (%) | 36/71 (50.1) | 10/71 (41.1) | 2/71 (2.8) |
Odds ratio (95% confidence interval) | 7.4 (4.5-12.4) | 2.2 (1.4-3.3) | 1.8 (0.9-3.4) |
Proportion without parasites in the placenta (%) | 40/292 (13.7) | 12/292 (4.1) | 0/292 (0) |
Proportion with parasites in the placenta (%) | 1/13 (7.6) | 3/13 (23.1) | 3/13 (23.1) |
Odds ratio (95% confidence interval) | 0.8 (0.3-2.2) | 1.8 (1.0-3.1) | NC |
NC: Not calculated