Table 2. Responses Myocytes Paced at a Frequency of 8 Hz.
| Parameter | Sham (n) | OVX (n) | p value |
|---|---|---|---|
| Fractional shortening (%) | 3.13 ± 0.5 (17) | 3.28 ± 0.3 (23) | p=0.795 |
| Time-to-peak contraction (msec) | 34.9 ± 1.2 (17) | 29.5 ± 1.1* (23) | p=0.004 |
| Time-to-50% relaxation (msec) | 27.3 ± 1.5 (17) | 21.1 ± 0.9* (23) | p=0.001 |
| Ca2+ transient (nM) | 67.3 ± 4.8 (14) | 92.4 ± 6.2* (22) | p=0.007 |
| Diastolic Ca2+ (nM) | 246.6 ± 11.7 (14) | 284.8 ± 10.7* (22) | p=0.025 |
| Rate of Ca2+ transient rise(nM/msec) | 3.60 ± 0.33 (14) | 5.18 ± 0.33* (22) | p=0.002 |
| Velocity to 50% transient decay (nM/msec) | 0.96 ± 0.08 (14) | 1.53 ± 0.10* (22) | p=0.001 |
Numbers represent mean ± SEM; values in brackets represent the number of cells. The * denotes significantly different from sham values, p<0.05.