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. 2013 Sep 18;8(9):e74661. doi: 10.1371/journal.pone.0074661

Figure 2. Inhibition of the anti-hyperalgesic effect of TAT-2ASCV by M100907 or bicuculline in carrageenan-injected rats.

Figure 2

Carrageenan-treated hyperalgesic rats were injected with M100907 (150 ng/rat) or bicuculline (3 µg/rat) in the absence or presence of the TAT-2ASCV peptide (100 ng/rat, i.t.). The vocalization thresholds to paw-pressure were measured up to 75 min after the injections (A). *P<0.05 and ***P<0.001, compared with values measured before the injections (time 0). (B) Area under the time-course (0-60 minutes) of vocalization threshold variations. *P< 0.05 and ***P<0.001 vs. NaCl + DMSO-treated group, # # # P<0.001 vs. TAT-2ASCV + DMSO-treated group.