Table 3. Results from regression analyses investigating relationship between post-deployment symptoms and gray matter volume.
| Structure | Side | BA | Grey Matter/Voxel | Volume (µL) | Coordinates | t | β | |||
| Term: AUDIT Score Polarity: Positive | ||||||||||
| Thalamus | L | 0.52±0.08 [0.37–0.68] | 552 | 7.5 | 27.3 | 11.7 | 3.62 | 0.019 | ||
| Term: AUDIT Score Polarity: Negative | ||||||||||
| Precentral Gyrus | R | 6 | 0.52±0.09 [0.35–0.74] | 472 | −7.3 | 11.2 | 66.3 | −3.47 | −0.024 | |
| Postcentral Gyrus | L | 5 | 0.35±0.08 [0.21–0.53] | 440 | 2.7 | 38.9 | 66.4 | −3.44 | −0.020 | |
| Superior/MiddleTemporal Gyrus | L | 21/22 | 0.51±0.10 [0.32–0.77] | 432 | 57.9 | 7.6 | −1.6 | −3.62 | −0.025 | |
| Term: CAPS Score Polarity: Positive | ||||||||||
| Cuneus | R | 18 | 0.52±0.09 [0.35–0.73] | 552 | −1.5 | 86.1 | 13.2 | 3.45 | 0.002 | |
| Term: CAPS Score Polarity: Negative | ||||||||||
| Inferior Temporal, Fusiform and Parahippocampal Gyrus | R | 20 | 0.55±0.09 [0.39–0.73] | 3608 | −38.2 | 30.4 | −29.5 | −3.82 | −0.003 | |
| Cerebellar Tonsil/Culmen | L | 0.67±0.10 [0.48–0.93] | 472 | 31.7 | 53.3 | −30.9 | −3.51 | −0.002 | ||
| Inferior Temporal Gyrus | L | 20 | 0.58±0.11 [0.37–0.85] | 392 | 30.3 | 5.8 | −45.1 | −3.53 | −0.003 | |
| Middle Frontal Gyrus | R | 8 | 0.50±0.10 [0.35–0.73] | 368 | −42.6 | −13.8 | 44.7 | −3.76 | −0.003 | |
Note: Gray matter volume determined using FSL implementation of voxel-based morphometry. Average t statistics and unstandardized regression coefficients were extracted for significant clusters of activation. Analyses were partial regressions investigating main effects of each predictor with N = 29 combat veterans from Operation Iraqi Freedom or Operation Enduring Freedom (OIF/OEF). CAPS = Clinician Administered PTSD Scale; AUDIT = Alcohol Use Identification Test.