Table 2. Boron concentration in wet weight in nuclei and cytoplasm of B16 melanoma cells in vitro determined by SIMS imaging analysis.
| Treatment – 30 ppm Boron equivalent of cis-ABCPCa | Boron concentration in Nucleus (µg/g mean ± SD) | Boron concentration in Cytoplasm (µg/g mean ± SD) | Nucleus to Nutrient Medium Boron Ratio |
| 1.0 hr | 83±18 | 94±23 | 2.8 |
| 2.5 hr | 149±43 | 162±39 | 5.0 |
| 4.0 hr | 225±29 | 230±50 | 7.5 |
| 4.0 hr followed by 30 min. in Nutrient Medium | 102±36 | 114±30 |
a
In each treatment, more than 30 cells were analyzed in 5–7 SIMS imaging fields for quantitative analysis.