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. 2013 Sep 18;8(9):e74174. doi: 10.1371/journal.pone.0074174

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© 2013 Leung et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A,B) H2BGFP is expressed in the epidermis and sweat glands before doxycycline treatment. (C,D) Sweat gland LRCs are found in the acinar gland region after 4 weeks of chase with doxycycline. (E,F) Tissue histology on sections with H&E staining. Abbreviations: LRCs, label-retaining cells; H2BGFP, histone 2B conjugated with green fluorescent protein; H&E, hematoxylin and eosin staining.