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. 2013 Sep 18;8(9):e74347. doi: 10.1371/journal.pone.0074347

Figure 7. Significant inter-residue correlations due to CL4 titrations of WT and F508del NBD1.

Figure 7

A. WT NBD1 residues that are significantly correlated with CL4-binding site residue G509 are mapped onto the NBD1 structure with a white-to-red gradient indicating increasing significance (decreasing p values). Those residues that are significantly correlated with H9 residue L644 of WT NBD1 are mapped onto the structure with an analogous white-to-purple gradient. B. Significant inter-residue correlations for the NBD1 C-terminal site residue L644 due to CL4 titrations of F508del NBD1 are mapped onto the NBD1 structure with a white-to-purple gradient. Non-significant correlations are in white, while unassigned and unanalyzed residues are in tan.