Figure 6. CRP is a positive regulator of LT secretion in vivo.

The wild-type (E2863 wt) and cAMP receptor protein deficient strain E2863ΔCRP) were appropriately diluted in PBS and orogastrically inoculated into infant mice. Three hours post-infection 8 small intestines per bacterial strain were collected and used for estimation of LT secretion by GM1-ELISA as described in Material and Methods. Bars represent the geometric mean and error bars represent the standard deviations of 3 independent experiments. A Student t test was used to calculate P values, *P<0.05.