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A, Lcn2 protein is more abundant in inguinal adipose tissue. B–D, Lcn2 protein expression in Epi-WAT (B), Ing-WAT (C), and serum Lcn2 (D) in normal mice under RCD and HFD conditions. E–J, Time course of RCD or HFD effect on body weight gain (E and F) and inguinal (G and I), and epididymal (H and J) fat mass increase in WT and Lcn2−/− mice. Results of E–J represent mean ± SE of 7 to 10 animals. *, P < .05; **, P < .01; WT vs Lcn2−/−.
