Table 6.
The Adjusteda Association of the Component Comorbidities of Charlson Index With Nonvariceal Bleeding
| Proportion of cases exposed, % | ORa | Lower 95% CI | Upper 95% CI | PAF,b% | |
|---|---|---|---|---|---|
| Myocardial infarction | 13.98 | 1.04 | 0.97 | 1.10 | 0.12 |
| Congestive cardiac disease | 19.90 | 1.49 | 1.41 | 1.58 | 1.95 |
| Peripheral vascular disease | 11.17 | 1.31 | 1.23 | 1.41 | 0.70 |
| Dementia | 8.98 | 1.40 | 1.30 | 1.50 | 1.00 |
| Chronic pulmonary disease | 31.80 | 1.11 | 1.06 | 1.16 | 1.10 |
| Cerebrovascular disease | 23.1 | 1.13 | 1.08 | 1.19 | 0.80 |
| Rheumatological disease | 10.13 | 1.06 | 0.99 | 1.13 | 0.17 |
| Uncomplicated diabetes | 17.88 | 1.01 | 0.96 | 1.06 | 0.04 |
| Hemiplegia | 4.73 | 1.79 | 1.62 | 1.97 | 0.67 |
| Renal disease | 14.42 | 1.71 | 1.61 | 1.82 | 1.74 |
| Diabetes with complications | 12.30 | 1.00 | 0.94 | 1.06 | −0.01 |
| Any malignancy | 13.11 | 1.21 | 1.14 | 1.28 | 0.78 |
| Lymphoproliferative disorders | 2.21 | 1.95 | 1.70 | 2.24 | 0.43 |
| Metastatic solid tumour | 5.89 | 2.35 | 2.14 | 2.57 | 1.29 |
| HIV/AIDS | 0.06 | 0.69 | 0.31 | 1.55 | −0.00 |
HIV/AIDS, human immunodeficiency virus/acquired immunodeficiency syndrome.
a
Adjusted for all other variables in this Table and Table 2 and matched for year, practice, and sex.
b
Sequential population attributable fractions: The estimates in each row are calculated separately conditional on all the other variables in the model. They should therefore not be interpreted as summing over the column to 100%. Sequential PAF estimates the additional proportion of nonvariceal bleeding cases attributable to each risk factor after cases attributable to all the other risk factors in the model have been removed.