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Serum urea on day 0 (before surgery), day 28 and day 56 for each group: sham surgery groups did not show any significant change in serum urea levels. SNX groups showed a significant rise in serum urea levels on day 28 and 56 compared to day 0 (*p < 0.05). At day 28 and 56, serum urea levels were significantly higher in P2Y2-R KO SNX compared to WT SNX mice (#p < 0.05) (mean ± SEM).
