Table 2. Classification results of the 28 SqCC cell lines to SqCC subtypes.
| |
Subtype rank |
ClaNC |
|
|||||
|---|---|---|---|---|---|---|---|---|
| Cell line | First subtype | Second subtype | First subtype | Permutaion P | Second subtype | Permutation P | Predicted | With drug data |
| NCI-H226 |
Secretory |
Primitive |
Secretory |
0.16 |
Basal |
0.457 |
Secretory |
y |
| EBC-1 |
Secretory |
Basal |
Basal |
0.426 |
Primitive |
0.277 |
Basal |
y |
| VMRC-LCP |
Basal |
Classical |
Basal |
0.033 |
Classical |
0.32 |
Basal |
|
| HCC-1588 |
Basal |
Primitive |
Basal |
0.082 |
Secretory |
0.595 |
Basal |
|
| RERF-LC-AI |
Primitive |
Secretory |
Primitive |
0.07 |
Secretory |
0.311 |
Primitive |
y |
| SK-MES-1 |
Primitive |
Secretory |
Basal |
0.293 |
Secretory |
0.318 |
Secretory |
y |
| NCI-H520 |
Classical |
Primitive |
Primitive |
0.076 |
Classical |
0.678 |
Primitive |
y |
| HCC-15 |
Classical |
Secretory |
Classical |
0.061 |
Basal |
0.528 |
Classical |
y |
| SW 900 |
Primitive |
Basal |
Secretory |
0.109 |
Basal |
0.25 |
Secretory |
y |
| LUDLU-1 |
Basal |
Classical |
Classical |
0.024 |
Basal |
0.077 |
Classical |
y |
| HARA |
Secretory |
Classical |
Basal |
0.308 |
Secretory |
0.557 |
Secretory |
y |
| KNS-62 |
Basal |
Classical |
Basal |
0.118 |
Classical |
0.551 |
Basal |
y |
| EPLC-272H |
Basal |
Primitive |
Basal |
0.114 |
Secretory |
0.339 |
Basal |
|
| HCC-95 |
Classical |
Secretory |
Classical |
0.009 |
Basal |
0.667 |
Classical |
|
| LC-1/sq-SF |
Classical |
NA |
Classical |
0.013 |
Basal |
0.688 |
Classical |
y |
| SW 1573 |
Secretory |
Primitive |
Primitive |
0.108 |
Secretory |
0.277 |
Primitive |
y |
| LC-1F |
Classical |
Basal |
Classical |
0.012 |
Primitive |
0.539 |
Classical |
|
| LOU-NH91 |
Secretory |
Primitive |
Secretory |
0.19 |
Primitive |
0.231 |
Secretory |
y |
| LK-2 |
Classical |
Primitive |
Primitive |
0.074 |
Classical |
0.585 |
Primitive |
|
| RERF-LC-Sq-1 |
Primitive |
Classical |
Secretory |
0.293 |
Primitive |
0.209 |
Primitive |
|
| HLF-a |
Primitive |
Classical |
Secretory |
0.063 |
Primitive |
0.233 |
Secretory |
|
| Calu-1 |
Primitive |
Secretory |
Secretory |
0.08 |
Basal |
0.583 |
Secretory |
y |
| NCI-H2170 |
Basal |
Classical |
Classical |
0.114 |
Primitive |
0.085 |
Classical |
y |
| Sq-1 |
Primitive |
NA |
Secretory |
0.129 |
Basal |
0.166 |
Secretory |
y |
| HCC-2814 |
Classical |
Basal |
Classical |
0.048 |
Basal |
0.369 |
Classical |
|
| HCC-1897 |
Secretory |
Primitive |
Secretory |
0.07 |
Basal |
0.39 |
Secretory |
|
| NCI-H1385 |
Classical |
Primitive |
Primitive |
0.069 |
Classical |
0.352 |
Primitive |
|
| NCI-H1869 | Basal | NA | Secretory | 0.244 | Basal | 0.303 | Basal | y |
Abbreviations: ClaNC=classification method to nearest centroids; SqCC=squamous cell lung cancer.