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. 2013 Aug 27;109(6):1657–1665. doi: 10.1038/bjc.2013.481

Figure 1.

Figure 1

Development of HCC-ART score in 1351 patients with non-malignant CLDs and HCC in the estimation group. (A) Area under curve of candidate's markers to discriminate patients with HCC from patients with liver cirrhosis. (B) Development of HCC-ART score combining Alb, age, AFP, ALP, and AST/ALT ratio, correlation between the different markers included in the score, and the final HCC-ART score. (C) Box plots of HCC-ART score to discriminate HCC from no fibrosis (F0), liver fibrosis (F1–F3), and liver cirrhosis (F4) patients. The whiskers indicate the highest and lowest values, and the line across the box indicates the median value. (D) The AUC of HCC-ART score to discriminate 227 patients with HCC from 341 patients with liver cirrhosis (F4). (E) The AUC of HCC-ART score to discriminate 227 patients with HCC from 676 patients with liver fibrosis (F1–F3). (F) The AUC of HCC-ART score to discriminate 227 patients with HCC from 107 patients with no liver fibrosis (F0). Abbreviations: AAR=AST−ALT ratio; AFP=α-fetoprotein; APRI=AST/platelets ratio index; Plat.=platelet count; T. bili=total bilirubin.