Table 5. Univariate (unadjusted) ordinal regression analysis showing predictors of increasing chronic radiation enteritis/proctitis severity in the whole cohort.

Variable	OR (95% CI)	P-value
Age	0.96 (0.94–0.98)	0.001
Cancer type (endometrial vs cervical)	0.49 (0.26–0.93)	0.028
History of diabetes/hypertension	1.57 (0.64–3.96)	0.312
History of previous IBS/diverticular disease	1.52 (0.53–4.31)	0.436
Smoking history	0.32 (0.17–0.77)	0.008
Stage of disease (cervix)	0.76 (0.42–1.36)	0.356
Stage of disease (endo)	0.78 (0.45–1.36)	0.388
NACT pre-chemoradiation (cervix)	1.58 (0.41–2.50)	0.976
Extended field RT (pelvic side wall boost/pa strip) (cervix)	0.37 (0.14–0.96)	0.041
Laparoscopic vs open hysterectomy (endo)	0.59 (0.21–1.65)	0.311
Chemo vs no chemo (endo)	0.95 (0.34–2.63)	0.921
P/PA node dissection (endo)	2.13 (0.58–7.75)	0.255
P/PA node dissection (cervix)	0.67 (0.24–1.85)	0.442
Surgical treatment (no vs yes)	0.22 (0.08–0.55)	0.001
‘Symptom cluster' at presentation
Factor 1	1.18 (0.86–1.63)	0.302
Factor 2	1.10 (0.80–1.51)	0.548
Factor 3	1.36 (1.00–1.86)	0.053

Abbreviations: CI=confidence interval; NACT=neo-adjuvant chemotherapy; OR=odds ratio; P/PA=pelvic/para-aortic node dissection; RT=Radiotherapy.