Table 5. Inter-relationships between the clinicopathological characteristics of patients with high grade inflammatory cell infiltrate primary operable invasive ductal breast cancer.
| Grade (P-value) | Involved lymph node (P-value) | ER status (P-value) | PR status (P-value) | HER-2 status (P-value) | Ki-67 status (P-value) | LVI (P-value) | CD68+ (P-value) | Tumour lymphocytic infiltrate (P-value) | CD8+ T-lymphocytic infiltrate (P-value) | CD138+ B-lymphocytic infiltrate | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Size (⩽20/ 21–50/>50 mm) |
0.001 |
<0.001 |
0.007 |
0.028 |
0.195 |
0.059 |
<0.001 |
0.924 |
0.109 |
0.540 |
0.134 |
| Grade (I/II/III) |
|
0.024 |
<0.001 |
<0.001 |
<0.001 |
0.002 |
0.001 |
0.006 |
<0.001 |
<0.001 |
<0.001 |
| Involved lymph node (0/1–3/>3) |
|
|
0.031 |
0.308 |
0.016 |
0.357 |
<0.001 |
0.923 |
0.017 |
0.911 |
0.102 |
| ER status (ER-/ER+) |
|
|
|
<0.001 |
<0.001 |
0.105 |
0.014 |
0.132 |
<0.001 |
0.003 |
<0.001 |
| PR status (PR-/PR+) |
|
|
|
|
<0.001 |
0.239 |
0.090 |
0.647 |
<0.001 |
0.205 |
0.001 |
| HER-2 status (HER-2 -/HER-2+) |
|
|
|
|
|
0.159 |
0.002 |
0.187 |
0.197 |
0.771 |
<0.001 |
| Ki-67 (Low Ki-67/High Ki-67) |
|
|
|
|
|
|
0.239 |
0.151 |
0.170 |
0.075 |
0.306 |
| Lymphovascular invasion (LVI-/LVI+) |
|
|
|
|
|
|
|
0.829 |
0.017 |
0.567 |
0.089 |
| Tumour macrophage infiltrate (tertiles) |
|
|
|
|
|
|
|
|
0.870 |
<0.001 |
0.007 |
| Tumour lymphocyte infiltrate (Low/high) |
|
|
|
|
|
|
|
|
|
0.969 |
0.024 |
| Tumour CD8+ T-lymphocytic infiltrate (tertiles) | <0.001 |
P-values <0.01 are shown in bold face.