Table 2.
Correlations of cytosolic YAP with clinicopathological features in invasive breast cancer
| Feature | N | Cytosolic YAP expression Negative N (%) | Positive N (%) | p-value |
|---|---|---|---|---|
| Histologic type | ||||
| IDC | 187 | 126 (67.4) | 61 (32.6) | 0.002 |
| ILC | 49 | 21 (42.9) | 28 (57.1) | |
| Histologic grade | ||||
| 1 | 36 | 25 (69.4) | 11 (30.6) | 0.626 |
| 2 | 76 | 46 (60.5) | 30 (39.5) | |
| 3 | 124 | 76 (61.3) | 48 (38.7) | |
| Tumor size (cm) | ||||
| ≤ 2 | 108 | 67 (62.0) | 41 (38.0) | 0.240 |
| > 2 and ≤5 | 97 | 65 (67.0) | 32 (33.0) | |
| > 5 | 30 | 15 (50.0) | 15 (50.0) | |
| MAI (per 2 mm2) | ||||
| ≤ 12 | 103 | 64 (62.1) | 39 (37.9) | 0.966 |
| ≥ 13 | 133 | 83 (62.4) | 50 (37.6) | |
| Lymph node status | ||||
| Negative | 97 | 57 (58.8) | 40 (41.2) | 0.426 |
| Positive | 125 | 80 (64.0) | 45 (36.0) | |