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Glioma cell lines were investigated for the methylation level of LINE1 element (Qiagen, Germany) for LNT 229, LN 18, and LNT 308. Temozolomide resistant strains of same cell lines that were obtained with treatment of increasing concentrations of the drug; exemplarily depicted is LNT 308 P (drug sensitive) and LNT 308 R (drug resistant).
