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In silico modeling of the SLURP1 wild type (a) and SLURP1 with the p.Cys99Tyr mutation (b). The model shows the possible structural differences between the mutant and wild-type proteins. The presence of the p.Cys99Tyr variation led to a new protein folding missing the loops conformation. Structures are determined from amino acid sequences with I-Tasser online server and figures produced with PyMOL viewer. The p.Cys99Tyr variation position is showed by red.
