. Author manuscript; available in PMC: 2013 Sep 19.

Published in final edited form as: Acc Chem Res. 2011 Jun 7;44(10):957–968. doi: 10.1021/ar200028a

TABLE 1.

List of Biomedically Relevant Agents Incorporated into NMOFs and Their Intended Applications

NMOF	Metal	Active Agent	Function	Ref
1	Tb³⁺		Drug Delivery	24
2/2a	Fe³⁺		Drug Delivery Optical Contrast	25
3/4	Gd³⁺	Gd³⁺	MRI Contrast	28
5	Gd³⁺	Gd³⁺	MRI Contrast	29
6	Mn²⁺	Mn²⁺	MRI Contrast	32
7	Mn²⁺	Mn²⁺ Rhodamine B	MRI contrast Optical Contrast	32
8	Fe³⁺	Busulfan Cidofovir	Drug Delivery	30
9	Fe³⁺	Fe³⁺ Busulfan Cidofovir AZT	MRI contrast Drug Delivery	30
10	Fe³⁺	Fe³⁺ Busulfan Cidofovir Doxorubicin Ibuprofen AZT	MRI Contrast Drug Delivery	30
11	Fe³⁺	AZT Cidofovir	Drug Delivery	30
12	Fe³⁺	None	None	30
13	Fe³⁺	Busulfan AZT Ibuprofen Caffeine	Drug Delivery	30
14/15	Zn²⁺/Zr⁴⁺		Optical Imaging	64
16	Gd³⁺		Optical Imaging	39
17/18	Cu²⁺/Zn²⁺	Iodine	CT Contrast	33
19	Zn²⁺	Doxorubicin SN-38 Camptothecin Daunomycin	Drug Delivery	36