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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Glia. 2013 Jul 8;61(9):1533–1541. doi: 10.1002/glia.22539

Figure 4. Lineage tracing with Aldh1L1 Cre mice labels neurons.

Figure 4

A) Anti-GFP antibody staining of mouse forebrain from and Aldh1L1 Cre line JD1884, crossed to a YFP reporter mouse, shows expression in glia throughout the parenchema, and in presumptive neuroblasts of the rostral migratory stream (box, right panel) and adjacent neurons in the olfactory bulb. B) In the neurogenic dentate gyrus (box, right panel), GFP is seen in glial cells in the SGZ (arrowhead) and neurons of the granule cell layer (arrows). C) Immunofluorescence for YFP (green) and a mix of neuronal markers (NeuN and NF200, red), reveals some upper layer cortical neurons also derive from Aldh1L1 expressing cells (white arrows).