Table 5.
GROUPS | Pre-occlusion | Occlusion | Reperfusion | ||||
---|---|---|---|---|---|---|---|
5 min | 15 min | 30 min | 5 min | 10 min | 15 min | ||
Temperature (°C) | |||||||
XXXI, 129S6, LPC | 36.9 ± 0.1 | 37.1 ± 0.1 | 37.0 ± 0.1 | 37.2 ± 0.1 | 37.0 ± 0.1 | 36.9 ± 0.1 | 36.9 ± 0.1 |
XXXII, B6/129P2, LPC | 36.9 ± 0.0 | 37.0 ± 0.0 | 37.0 ± 0.0 | 37.0 ± 0.0 | 37.0 ± 0.0 | 37.0 ± 0.0 | 37.0 ± 0.1 |
XXXIII, B6/129F2, LPC sham | 37.2 ± 0.1 | 37.1 ± 0.1 | 37.1 ± 0.1 | 37.1 ± 0.1 | 37.0 ± 0.1 | 36.9 ± 0.1 | 36.9 ± 0.2 |
XXXIV, B6/129F2, LPC | 37.1 ± 0.1 | 37.2 ± 0.1 | 37.1 ± 0.1 | 37.0 ± 0.1 | 36.8 ± 0.2 | 37.0 ± 0.2 | 37.1 ± 0.1 |
XXXV, B6/129/D2, LPC | 37.0 ± 0.1 | 37.1 ± 0.0 | 37.0 ± 0.1 | 37.1 ± 0.1 | 37.1 ± 0.1 | 37.2 ± 0.1 | 37.2 ± 0.2 |
XXXVI, B6/DBA, LPC | 36.8 ± 0.2 | 37.0 ± 0.1 | 37.0 ± 0.1 | 37.0 ± 0.1 | 36.9 ± 0.9 | 37.0 ± 0.1 | 37.0 ± 0.1 |
XXXVII, BALB/c, LPC | 37.2 ± 0.1 | 37.4 ± 0.1 | 37.3 ± 0.1 | 37.1 ± 0.1 | 37.1 ± 0.1 | 37.1 ± 0.2 | 37.3 ± 0.2 |
XXXVIII, BPH, LPC | 36.8 ± 0.0 | 37.2 ± 0.1 | 37.0 ± 0.1 | 37.2 ± 0.1 | 36.9 ± 0.1 | 37.0 ± 0.1 | 37.1 ± 0.1 |
XXXIX, B6/J, LPC | 37.0 ± 0.1 | 37.2 ± 0.1 | 37.1 ± 0.1 | 37.1 ± 0.1 | 36.9 ± 0.1 | 37.1 ± 0.2 | 37.2 ± 0.1 |
XL, FVB/N, LPC | 36.9 ± 0.1 | 37.1 ± 0.1 | 37.2 ± 0.1 | 37.1 ± 0.1 | 37.0 ± 0.1 | 37.0 ± 0.1 | 37.0 ± 0.1 |
XLI, FVB/B6, LPC | 37.0 ± 0.1 | 37.1 ± 0.0 | 37.0 ± 0.1 | 37.0 ± 0.1 | 37.0 ± 0.1 | 37.1 ± 0.2 | 37.1 ± 0.1 |
XLII, ICR, LPC sham | 37.1 ± 0.1 | 37.2 ± 0.1 | 37.3 ± 0.1 | 37.1 ± 0.1 | 37.1 ± 0.1 | 37.1 ± 0.1 | 37.1 ± 0.1 |
XLIII, ICR, LPC | 36.9 ± 0.1 | 37.1 ± 0.1 | 37.1 ± 0.1 | 36.9 ± 0.1 | 36.9 ± 0.0 | 36.9 ± 0.1 | 36.8 ± 0.1 |
Heart rate (beats/min) | |||||||
XXXI, 129S6, LPC | 608 ± 21 | 624 ± 22 | 637 ± 21 | 652 ± 22 | 640 ± 23 | 634 ± 25 | 645 ± 25 |
XXXII, B6/129P2, LPC | 590 ± 14 | 619 ± 11 | 611 ± 11 | 608 ± 10 | 618 ± 10 | 612 ± 12 | 620 ± 10 |
XXXIII, B6/129F2, LPC sham | 577 ± 29 | 567 ± 24 | 565 ± 24 | 585 ± 33 | 601 ± 34 | 583 ± 33 | 607 ± 28 |
XXXIV, B6/129F2, LPC | 552 ± 25 | 559 ± 22 | 565 ± 22 | 560 ± 24 | 558 ± 26 | 569 ± 24 | 578 ± 27 |
XXXV, B6/129/D2, LPC | 563 ± 26 | 595 ± 32 | 586 ± 36 | 588 ± 32 | 590 ± 27 | 596 ± 23 | 616 ± 38 |
XXXVI, B6/DBA, LPC | 632 ± 19 | 663 ± 25 | 666 ± 34 | 671 ± 42 | 663 ± 41 | 675 ± 41 | 657 ± 47 |
XXXVII, BALB/c, LPC | 609 ± 35 | 609 ± 20 | 616 ± 27 | 607 ± 33 | 621 ± 29 | 627 ± 19 | 654 ± 62 |
XXXVIII, BPH, LPC | 693 ± 15 | 720 ± 12 | 701 ± 15 | 715 ± 8 | 707 ± 17 | 684 ± 28 | 701 ± 12 |
XXXIX, B6/J, LPC | 569 ± 28 | 613 ± 40 | 597 ± 39 | 606 ± 34 | 613 ± 32 | 633 ± 29 | 644 ± 28 |
XL, FVB/N, LPC | 606 ± 9 | 661 ± 19 | 670 ± 13 | 678 ± 20 | 699 ± 19 | 707 ± 13 | 717 ± 35 |
XLI, FVB/B6, LPC | 562 ± 26 | 591 ± 20 | 586 ± 20 | 608 ± 16 | 610 ± 29 | 593 ± 34 | 597 ± 19 |
XLII, ICR, LPC sham | 637 ± 15 | 666 ± 14 | 697 ± 15 | 686 ± 16 | 690 ± 17 | 674 ± 14 | 674 ± 16 |
XLIII, ICR, LPC | 566 ± 9 | 618 ± 17 | 620 ± 16 | 636 ± 15 | 640 ± 16 | 634 ± 21 | 635 ± 21 |
Data are means ± SEM. Measurements of rectal temperature and heart rate were taken before the 30-min coronary occlusion (pre-occlusion), at 5, 15 and 30 min into the 30-min occlusion, and at 5, 15 and 30 min after reperfusion. Rectal temperature was continuously monitored and carefully controlled throughout the experiment, as detailed in the text.