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. Author manuscript; available in PMC: 2014 Jan 1.
Published in final edited form as: Psychopharmacology (Berl). 2012 Aug 4;225(1):187–199. doi: 10.1007/s00213-012-2807-9

Figure 7.

Figure 7

Effects of chronic treatment with 10 mg/kg of morphine (10 MS) or with NMDAR antagonists on stimulus effects of morphine (MS). Rats were trained to discriminate 3.2 mg/kg MS and saline and then received chronic treatment, shown in column titles, b.i.d. for 7 days. Tests of cumulative doses of MS were conducted before treatment and 12 h after the last injection on Day 7 of treatment; i.e., on Day 8 (D8). On test days, rats received SAL 30 min before the tests. Other details as in Fig. 5. Text in italics identifies the −30-min pretreatment: SAL saline