Table 3. Analysis of factors that influence EGFR FISH phenotype in patients with NSCLC.
| Variable | EGFR mutation | FISH phenotype [cases (%)] |
P | |
| Negative | Positive | |||
| Gender | ||||
| Male | - | 54 (48) | 58 (52) | 0.001 |
| + | 3 (11) | 23 (89) | ||
| Female | - | 14 (52) | 13 (48) | 0.001 |
| + | 6 (15) | 34 (85) | ||
| Age (years) | ||||
| ≥ 59 | - | 34 (44) | 44 (56) | 0.011 |
| + | 6 (18) | 27 (82) | ||
| <59 | - | 34 (56) | 27 (44) | <0.001 |
| + | 3 (9) | 30 (91) | ||
| Smoking status | ||||
| Ever | - | 46 (45) | 56 (55) | 0.036 |
| + | 3 (18) | 14 (82) | ||
| Never | - | 22 (60) | 15 (40) | <0.001 |
| + | 6 (12) | 43 (88) | ||
| Histological type | ||||
| ADC | - | 41 (49) | 43 (51) | <0.001 |
| + | 9 (14) | 54 (86) | ||
| Non-ADC | - | 27 (49) | 28 (51) | 0.241 |
| + | 0 (0) | 3 (100) | ||
| Differentiation | ||||
| Grade 1 | - | 7 (58) | 5 (42) | 0.294 |
| + | 1 (20) | 4 (80) | ||
| Grade >1 | - | 61 (48) | 66 (52) | <0.001 |
| + | 8 (13) | 53 (87) | ||
| Stage | ||||
| Early (IA+IB) | - | 35 (57) | 26 (43) | 0.001 |
| + | 4 (17) | 20 (83) | ||
| Medium (IIA+IIB+IIIA) | 11 A) | 22 (40) | 33 (60) | 0.010 |
| + | 3 (11) | 23 (89) | ||
| Advanced (IIIB+IV) | 11 (48) | 12 (52) | 0.037 | |
| + | 2 (12) | 14 (88) | ||
Abbreviations as in Table 1.