Table 2. Association between RRM1 expression and clinicopathologic features of 48 NPC patients.
Characteristic | RRM1–negative | RRM1-positive | χ2 test P value |
Gender | 0.975 | ||
Men | 24 | 14 | |
Women | 7 | 3 | |
Age (years) | 0.632 | ||
≥ 47 | 15 | 7 | |
< 47 | 16 | 10 | |
ECOG performance status | 0.202 | ||
0 | 16 | 12 | |
1 | 15 | 5 | |
Prior radiotherapy | 0.272 | ||
Yes | 23 | 10 | |
No | 8 | 7 | |
Prior chemotherapy cycles | 0.867 | ||
≤ 6 | 19 | 10 | |
> 6 | 12 | 7 | |
Number of prior chemotherapy regimens | 0.339 | ||
1 | 10 | 3 | |
≥ 2 | 18 | 13 | |
Number of distant metastases | 0.464 | ||
1 | 18 | 8 | |
≥ 2 | 13 | 9 | |
Gemcitabine cycles | 0.839 | ||
≤ 4 | 21 | 12 | |
> 4 | 10 | 5 |
Footnotes as in Table 1