Table 2. Distribution of TNF-α genotypes and frequencies in HCV-infected patients and healthy controls.
Genotype | Healthy controls (n = 45) | Cirrhosis patients (n = 45) | HCC patients (n = 45) |
-308 G/A genotype | |||
G/G | 25 (56) | 39 (87)a | 42 (94)a |
G/A | 13 (29) | 3 (7)b | 2 (4)a |
A/A | 7 (15) | 3 (6) | 1 (2)c |
GA+AA | 38 (84) | 42 (93)a | 44 (97)a |
-308 G/A alleles | |||
G | 63 (70) | 81 (90) | 86 (96)c |
A | 27 (30) | 9 (10)a | 4 (4)a |
All data are presented as cases (%). aP< 0.001, bP < 0.01, cP < 0.05, vs. controls.