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. 2012 May;31(5):248–256. doi: 10.5732/cjc.011.10383

Figure 2. Effect of YC-1 on the HIF-1α expression in MDA-MB-468 cells.

Figure 2.

Under normoxic conditions, 10 µmol/L YC-1 inhibited HIF-1α mRNA expression (A), but had no effect on HIF-1α protein(B). Under hypoxic conditions, YC-1 inhibited HIF-1α mRNA(C) and protein expression (D) in a dose-dependent manner. *P < 0.05, **P < 0.01, vs. control.